KROK 1 2021 – Question 13 · KROK (Medicine) · Pathophysiology

A man presents with decreased vasopressin synthesis, which causes polyuria and results in marked dehydration. What is the most likely polyuria mechanism in this case?

  1. A. Decreased tubular reabsorption of protein
  2. B. Decreased tubular reabsorption of water
  3. C. Increased hydrostatic pressure
  4. D. Disturbed glucose reabsorption
  5. E. Disturbed tubular reabsorption of Na ions
Hint

Recall what vasopressin normally does to the permeability of the collecting ducts through aquaporin channels, and what happens when it is missing.

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