KROK 1 2021 – Question 69 · KROK (Medicine) · Pathophysiology

1.5 weeks after a severe case of streptococcal tonsillitis, a 24-year-old man developed face edema and elevated blood pressure. He presents with hematuria and proteinuria of 1.2 g/L. In the blood, antistreptococcal antibodies and low levels of complement components are detected. In this case, nephropathy has been caused by immune complexes, accumulations of which can most likely be found in the microvasculature of:

  1. A. Henle loop
  2. B. Pyramids
  3. C. Descending tubules
  4. D. Glomeruli
  5. E. Proximal tubules
Hint

Think about where circulating immune complexes are filtered and trapped in the kidney, in the capillary tufts that form the primary ultrafiltrate.

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