KROK 1 2021 – Question 4 · KROK (Medicine) · Biological Chemistry

Patients with B₁₂-deficiency anemia develop degenerative processes in the posterior and lateral columns of the spinal cord (funicular myelosis). In this case, the damage to the axons is caused by the disturbed formation of:

  1. A. Myelin
  2. B. Noradrenaline
  3. C. Acetylcholine
  4. D. Dopamine
  5. E. Serotonin
Hint

Vitamin B₁₂ is a cofactor in reactions of fatty-acid and methyl-group metabolism; think about which component of the long spinal tracts is built and maintained by such reactions.

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