KROK 1 2023 – Question 110 · KROK (Medicine) · Pharmacology

A patient diagnosed with essential hypertension was undergoing hypothiazide (hydrochlorothiazide) treatment. He complains of general weakness, loss of appetite, and palpitations. Examination reveals muscle hypotonia, flaccid paralyses, and decreased intestinal peristalsis. What is the likely cause of the patient’s condition?

  1. A. Hypercalcemia
  2. B. Hyponatremia
  3. C. Hyperkalemia
  4. D. Hypokalemia
  5. E. Hyperuricemia
Hint

Think about which important intracellular ion a thiazide diuretic wastes in the urine, and how its deficit affects skeletal muscle, gut motility and the heart.

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