KROK 1 2023 – Question 144 · KROK (Medicine) · Pharmacology

A patient has been diagnosed with psychosis. After two weeks of receiving pharmacotherapy, the patient's condition improved. However, the patient soon developed rigidity, tremors, and hypokinesia. What drug causes these complications?

  1. A. Imizin (Imipramine)
  2. B. Diphenin (Phenytoin)
  3. C. Chlordiazepoxide
  4. D. Sydnocarb (Mesocarb)
  5. E. Aminazine (Chlorpromazine)
Hint

Consider the antipsychotic class that blocks dopamine D₂ receptors in the nigrostriatal pathway, causing parkinsonian side effects after a good initial response.

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