KROK 1 2023 – Question 78 · KROK (Medicine) · Pharmacology
A person was hospitalized with morphine poisoning. In cases of acute morphine poisoning, a specific antagonist — naloxone — is used. What is the main factor in the development of antagonistic action in such cases?
- A. Direct stimulation of the respiratory center
- B. Decreased sensitivity of the body to morphine
- C. Sharp acceleration of morphine metabolism
- D. Reflex excitation of the respiratory center
- E. Competition for binding to opioid receptors
Hint
Focus on where naloxone acts and whether it needs any effect of its own (on the respiratory centre, on morphine metabolism, on tissue sensitivity) to reverse morphine poisoning.
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