KROK 1 2023 – Question 54 · KROK (Medicine) · Pathomorphology

The biopsy material obtained from the enlarged lymph node of a patient with a subfebrile temperature contains numerous granulomas with caseous necrosis in the center. The areas of necrosis are surrounded by epithelioid cells, Langhans giant multinucleated cells, and lymphocytes. What disease can be characterized by these pathohistological changes?

  1. A. Lymphogranulomatosis
  2. B. Lymphosarcoma
  3. C. Tuberculosis
  4. D. Lymphocytic leukemia
  5. E. —
Hint

Look at the combination of central caseous necrosis, epithelioid cells and a particular kind of multinucleated giant cell: it is the signature of one chronic granulomatous infection.

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