KROK 1 2023 – Question 38 · KROK (Medicine) · Pharmacology
A patient with leukemia was prescribed 5-fluorouracil. What is the mechanism of action of this drug?
- A. DNase stimulation
- B. DNA synthesis inhibition
- C. Translation inhibition
- D. Transcription inhibition
- E. Replication catalysis
Hint
Think of an antimetabolite that mimics a pyrimidine base and blocks formation of the thymidine nucleotide needed by rapidly dividing cells.
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