KROK 1 2023 – Question 16 · KROK (Medicine) · Microbiology, Virology, and Immunology

A repeated Widal agglutination test shows an increase from 1:100 to 1:400 in the titers of antibodies to S. typhi O-antigens in the patient's serum. How can the obtained results be interpreted?

  1. A. The patient was previously vaccinated against typhoid fever
  2. B. The patient is a chronic carrier of typhoid microbes
  3. C. The patient has a past history of typhoid fever
  4. D. The patient has typhoid fever
  5. E. The patient is an acute carrier of typhoid microbes
Hint

Consider what a fourfold or greater rise in antibody titre between paired sera taken days apart indicates about the timing of the infection.

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