KROK 1 2023 – Question 35 · KROK (Medicine) · Microbiology, Virology, and Immunology

A 10-year-old child underwent a Mantoux test (with tuberculin). After 48 hours, a papule up to 8 mm in diameter appeared at the site of tuberculin injection. What type of hypersensitivity reaction developed after administration of tuberculin?

  1. A. Type IV hypersensitivity reaction
  2. B. Arthus reaction
  3. C. Atopic reaction
  4. D. Type II hypersensitivity reaction
  5. E. Serum sickness
Hint

Consider the timing of the response, which appears only after two days, and whether antibodies or sensitized T lymphocytes mediate a skin reaction to tuberculin.

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