KROK 1 2023 – Question 8 · KROK (Medicine) · Pharmacology
A 49-year-old patient complains of persistently elevated blood pressure (155/120 mm Hg). The recommended hypotensive therapy, lasting for a month, was ineffective. Additional examination detected hypernatremia, hypochloremia, and adrenal hyperplasia. The diagnosis of primary hyperaldosteronism was made. Because surgical treatment was impossible in this case, the patient was recommended a pharmacological therapy with a mineralocorticoid receptor antagonist. What drug was recommended for the patient?
- A. Spironolactone
- B. Captopril
- C. Metoprolol
- D. Losartan
- E. Amlodipine
Hint
Think of the drug that competes with aldosterone at its intracellular receptor in the distal nephron, retaining potassium while promoting sodium excretion.
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