KROK 1 2020 – Question 48 · KROK (Medicine) · Pathophysiology
A lab rat has subcutaneously received mercury(II) chloride in the amount of 5 mg/kg. 24 hours later the plasma creatinine concentration increased several times. What mechanism of retention azotemia is observed in this case?
- A. Increased glomerular filtration
- B. Decreased glomerular filtration
- C. Increased creatinine secretion in the renal tubules
- D. Increased creatinine reabsorption
- E. Increased creatinine production in the muscles
Hint
Think about how the kidney handles creatinine, and which change in that handling could make it pile up in plasma after acute poisoning of the tubules.
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