KROK 1 2020 – Question 71 · KROK (Medicine) · Pathophysiology

A 29-year-old man complains of headache, swelling, weight gain, low urine output, and marked weakness. Laboratory testing revealed increased concentration of TSH. The levels of estrogen, growth hormone, glucose, urea, and creatinine are normal. What medical condition corresponds with these signs?

  1. A. Hypothyroidism
  2. B. Alimentary obesity
  3. C. Glomerulonephritis
  4. D. Hyperthyroidism
  5. E. Acromegalia
Hint

Follow the feedback loop: what does a raised TSH imply about the output of the gland it stimulates, and how would that explain fluid retention and weight gain?

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