KROK 1 2020 – Question 11 · KROK (Medicine) · Biological Chemistry
Secretion of orotic acid many times exceeds the norm in patients with hereditary orotic aciduria. This pathology is associated with disturbed synthesis of:
- A. Purine nucleotides
- B. Pyrimidine nucleotides
- C. Uric acid
- D. Urea
- E. Biogenic amines
Hint
Orotic acid is an intermediate, so ask which biosynthetic pathway it lies on and what that pathway ultimately produces.
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