KROK 1 2019 – Question 163 · KROK (Medicine) · Histology, Cytology, and Embryology
A 14-year old girl presents to the emergency department for evaluation of an “infected leg.” She states there is no history of trauma but mentions she had a history of sickle cell disease. On physical examination, her upper part of right shin is very painful, red, swollen and hot. Her temperature is 39.2°C. An X-ray shows focal bony lysis and loss of trabecular architecture in the metaphysis of right tibia. Increased activity of which of the following cells is the most likely cause of bone reabsorption in this patient?
- A. Osteocytes
- B. Osteoblasts
- C. Chondroblasts
- D. Osteoclasts
- E. Chondrocytes
Hint
Think about how inflammatory mediators from an infected metaphysis shift the balance of bone remodeling and which remodeling cell they stimulate.
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