KROK 1 2019 – Question 177 · KROK (Medicine) · Histology, Cytology, and Embryology

An unidentified surgical specimen is received for histopathologic analysis. A portion of the specimen is cut and stained with hematoxylin and eosin. Under the microscope, you see an organ encapsulated by dense connective tissue that extends to the deeper areas by way of the trabecular extensions. The organ can be subdivided into two regions: a cortex with lymphoid nodules and medulla with medullary cords populated by plasma cells, B-cells and T-cells. Which of the following structures is most likely the origin of this surgical specimen?

  1. A. Bone marrow
  2. B. Lymph node
  3. C. Thymus
  4. D. Spleen
  5. E. Tonsils
Hint

Compare the capsule, outer nodules and inner cords with the architecture of each immune organ, noting which have a cortex and medulla and where nodules sit within them.

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