KROK 1 2019 – Question 40 · KROK (Medicine) · Biological Chemistry

Patients with ischemic heart disease are usually prescribed small doses of aspirin. This drug inhibits synthesis of platelet aggregation activator, thromboxane A2. What substance is this activator synthesized from?

  1. A. Malonic acid
  2. B. Arachidonic acid
  3. C. Glutamic acid
  4. D. Homogentisic acid
  5. E. Acetic acid
Hint

Aspirin works by blocking an enzyme; ask what the substrate of that enzyme is and where in the cell it is stored before it is released.

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