KROK 1 2019 – Question 46 · KROK (Medicine) · Biological Chemistry

A 3-year-old child with elevated body temperature has taken aspirin and developed increased hemolysis of erythrocytes. In this case hemolytic anemia can be caused by congenital deficiency of the following enzyme:

  1. A. Glycerol-phosphate dehydrogenase
  2. B. Gamma-glutamyl transferase
  3. C. Glycogen phosphorylase
  4. D. Glucose 6-phosphate dehydrogenase
  5. E. Glucose 6-phosphatase
Hint

Think about which erythrocyte pathway generates the reducing power that protects cells from oxidant drugs, and which of its enzymes could be missing.

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