KROK 1 2019 – Question 2 · KROK (Medicine) · Biological Chemistry
A patient, who has been subsisting exclusively on polished rice, has developed polyneuritis due to thiamine deficiency. What substance is an indicator of such avitaminosis, when it is excreted with urine?
- A. Malate
- B. Pyruvic acid
- C. Methylmalonic acid
- D. Uric acid
- E. Phenyl pyruvate
Hint
Ask which metabolic reaction depends on thiamine pyrophosphate as its coenzyme, and therefore which substrate would build up and spill into urine when that reaction is impaired.
The answer, the explanation and a note on every option are available once you log in. The account is free: topic tests, a mock exam, mistake review and statistics.
More questions on Biological Chemistry
- Ammonia is extremely toxic for human CNS. What is the main way of ammonia neutralization in the nervous tissue?
- A patient presents with an acute attack of cholelithiasis. Laboratory examination of the patient’s feces will show the following in this case:
- During diabetes mellitus and starvation, the number of acetone bodies in blood increases. These bodies are used as a source of energy and are…
- A 45-year-old woman exhibits no signs of diabetes mellitus, but her fasting blood glucose levels are elevated (7.2 mmol/L). What should be measured…
- Examination of a patient shows decreased leukocyte and erythrocyte count and low hemoglobin levels in peripheric blood, as well as appearance of…
- A newborn presents with weak suckling, frequent vomiting, and hypotonia. Blood and urine citrulline are very high. What metabolic process is…