KROK 1 2018 – Question 176 · KROK (Medicine) · Pathomorphology

When examining a biopsy material obtained from the thyroid gland, the pathologist discovered lymphocyte infiltration of the thyroid tissues and destruction of the parenchymal elements. Diffuse lymphocyte infiltration with lymphoid follicles was detected in the stroma. What is the most likely diagnosis?

  1. A. Hashimoto’s thyroiditis (chronic lymphocytic thyroiditis)
  2. B. Undifferentiated thyroid carcinoma
  3. C. Papillary thyroid cancer
  4. D. Solid adenoma of the thyroid
  5. E. Graves’ disease (toxic diffuse goiter)
Hint

Consider what a diffuse infiltrate of lymphocytes with follicle formation and loss of the gland's own cells implies about the kind of process that is damaging the tissue.

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