KROK 1 2018 – Question 197 · KROK (Medicine) · Pathomorphology
Autopsy of a 50-year-old woman, who had been suffering from systemic connective tissue disease, reveals small dense kidneys with lumpy surface. Microscopy of the renal glomeruli detects there foci of fibrinoid necrosis, hyaline thrombi, hematoxylin bodies, and so-called “wire loop thickening” of the basement membranes. What disease can be characterized by such changes in the kidneys?
- A. Scleroderma
- B. Dermatomyositis
- C. Systemic lupus erythematosus
- D. Rheumatism
- E. Rheumatoid arthritis
Hint
Link the hallmark glomerular findings in the stem to a single multisystem autoimmune disease in which immune complexes deposit along the basement membranes.
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