KROK 1 2018 – Question 59 · KROK (Medicine) · Biological Chemistry

Blood of the patients with diabetes mellitus shows increased content of free fatty acids. Name the most likely cause of this:

  1. A. Activation of ketone bodies utilization
  2. B. Accumulation of palmitoyl-CoA in cytosol
  3. C. Increased activity of adipose triglyceride lipase
  4. D. Activation of apoA1, apoA2, and apoA4 apolipoprotein synthesis
  5. E. Decreased activity of plasma phosphatidylcholine-cholesterolacyltransferase
Hint

Think about what loss of insulin's braking effect does to the breakdown of storage fat in the depots, and what is then released into the circulation.

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