KROK 1 2018 – Question 9 · KROK (Medicine) · Biological Chemistry
The first-aid center has received a victim of a traffic accident diagnosed with closed displaced fracture of the middle third of the thigh. For repositioning of bone fragments the patient received 10 ml of 2% dithylinum solution intravenously, which resulted in prolonged period of apnoea and muscle relaxation. What enzyme is deficient, resulting in such pharmacogenetic enzymopathy?
- A. Pseudocholinesterase
- B. Uridine diphosphate glucuronyltransferase
- C. Methemoglobin reductase
- D. Glucose 6-phosphate dehydrogenase
- E. N-acetyltransferase
Hint
Think about which plasma enzyme normally hydrolyzes this short-acting muscle relaxant, and what an inherited defect in it would do to the duration of paralysis.
The answer, the explanation and a note on every option are available once you log in. The account is free: topic tests, a mock exam, mistake review and statistics.
More questions on Biological Chemistry
- Collagenosis patients typically present with connective tissue destruction processes. The presence of these processes can be confirmed by the…
- A 42-year-old man with gout presents with high content of uric acid in blood. The patient was prescribed allopurinol to lower the concentration of…
- Nitrogen is being excreted from the body mainly as urea. When activity of a certain enzyme in the liver is low, it results in inhibition of urea…
- People, who for a long time remained in hypodynamic state, develop intense pain in the muscles after a physical exertion. What is the most likely…
- A patient suffers from hepatic cirrhosis. What substance excreted in urine should be analyzed to characterize the antitoxic function of liver?
- Blood of the patients with diabetes mellitus shows increased content of free fatty acids. Name the most likely cause of this: