KROK 1 2018 – Question 3 · KROK (Medicine) · Pathophysiology
After a case of sepsis a 27-year-old woman developed ”bronzed” skin discoloration characteristic of Addison’s disease. Hyperpigmentation mechanism in this case is based on increased secretion of:
- A. β-lipotropin
- B. Gonadotropin
- C. Thyroid-stimulating hormone
- D. Somatotropin
- E. Melanocyte-stimulating hormone
Hint
After adrenal failure the loss of negative feedback makes the pituitary overproduce a family of peptides cut from one precursor; decide which of them darkens the skin.
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