KROK 1 2018 – Question 18 · KROK (Medicine) · Pathophysiology
A lab rat has subcutaneously received mercury(II) chloride in the amount of 5 mg/kg. 24 hours later the plasma creatinine concentration increased several times. What mechanism of retention azotemia is observed in this case?
- A. Increased creatinine reabsorption
- B. Increased creatinine production in the renal tubules
- C. Increased creatinine production in the muscles
- D. Increased glomerular filtration
- E. Decreased glomerular filtration
Hint
Plasma creatinine rises when its production increases or when its excretion falls; decide which applies after an acute nephrotoxic poisoning.
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