KROK 1 2018 – Question 20 · KROK (Medicine) · Pathophysiology

A 63-year-old man suffers from esophageal carcinoma, presents with metastases into the mediastinal lymph nodes and cancerous cachexia. What pathogenetic stage of neoplastic process is observed in the patient?

  1. A. Progression
  2. B. Promotion
  3. C. Initiation
  4. D. Transformation
  5. E. -
Hint

Use the clinical findings of spread to distant sites and systemic wasting to decide how far the tumour has advanced along the sequence of carcinogenesis.

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