KROK 1 2017 – Question 189 · KROK (Medicine) · Biological Chemistry
A 52-year-old man presents with fever and pain in the joints. Both of his first metatarsophalangeal articulations are deformed, swollen, and reddened. Blood urea is high. The patient is diagnosed with gout. What is the main developmental factor in the pathogenesis of this disease?
- A. Citrullinuria
- B. Hyperaminoacidemia
- C. Argininosuccinic aciduria
- D. Hyperazotemia
- E. Hyperuricemy
Hint
Gout is a disorder of purine metabolism; decide which raised blood metabolite comes from that pathway rather than from protein or amino acid breakdown.
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