KROK 1 2017 – Question 148 · KROK (Medicine) · Biological Chemistry

Streptomycin and other aminoglycosides prevent the joining of formylmethionyl-tRNA by bonding with the 30S ribosomal subunit. This effect leads to disruption of the following process:

  1. A. Translation initiation in procaryotes
  2. B. Replication initiation in procaryotes
  3. C. Translation initiation in eucaryotes
  4. D. Transcription initiation in procaryotes
  5. E. Transcription initiation in eucaryotes
Hint

Use the clues in the stem (ribosomal subunit size, formylated methionyl-tRNA) to decide which organisms and which macromolecular process, DNA, RNA or protein synthesis, is disrupted.

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