KROK 1 2017 – Question 118 · KROK (Medicine) · Biological Chemistry
An unconscious patient was delivered by ambulance to the hospital. On objective examination the patient was found to have no reflexes, periodical convulsions, irregular breathing. After laboratory examination the patient was diagnosed with hepatic coma. Disorders of the central nervous system develop due to the accumulation of the following metabolite:
- A. Urea
- B. Bilirubin
- C. Glutamine
- D. Ammonia
- E. Histamine
Hint
Think about the liver's role in handling nitrogen waste from amino acid breakdown, and which listed compound is the toxic one that reaches the brain when that role fails.
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