KROK 1 2016 – Question 194 · KROK (Medicine) · Pathophysiology
A patient is 20 years old, an athlete. He addressed a doctor with complaints of fatigue, fever up to 38°C - 40°C. Objectively: the liver and spleen are enlarged, lymph nodes on palpation are slightly enlarged, dense, painless. Blood test: Hb- 100 g/l; erythrocytes - 2,9 · 10¹²/l; leukocytes 4,4 · 10⁹/l. Leukogram: 68% of blast cells. Cytochemical investigation of blast cells revealed negative reactions to glycogen, peroxidase, non-specific esterase, lipids. Name this disease:
- A. Acute megakaryoblastic leukemia
- B. Acute monoblastic leukemia
- C. Acute lymphoblastic leukemia
- D. Acute undifferentiated leukemia
- E. Acute myeloid leukemia
Hint
Use the cytochemical stains to decide which cell line the blasts belong to, and consider what it means when none of the usual reactions is positive.
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