KROK 1 2016 – Question 12 · KROK (Medicine) · Biological Chemistry

A 53-year-old man is diagnosed with Paget’s disease. Concentration of oxyproline in daily urine is sharply increased, which primarily means intensified disintegration of:

  1. A. Albumin
  2. B. Collagen
  3. C. Hemoglobin
  4. D. Keratin
  5. E. Fibrinogen
Hint

Urinary oxyproline comes from the breakdown of a protein that is rich in this post-translationally modified amino acid; think which protein that is.

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