KROK 1 2015 – Question 170 · KROK (Medicine) · Biological Chemistry

Biochemical analysis of an infant’s erythrocytes revealed evident glutathione peroxidase deficiency and low concentration of reduced glutathione. What pathological condition can develop in this infant?

  1. A. Iron-deficiency anemia
  2. B. Hemolytic anemia
  3. C. Megaloblastic anemia
  4. D. Sicklemia
  5. E. Pernicious anemia
Hint

Think about what protects erythrocyte membranes and hemoglobin from peroxides and what happens to red cells that lose this defence.

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