KROK 1 2015 – Question 160 · KROK (Medicine) · Biological Chemistry
Cholesterol content in blood serum of a 12-year-old boy is 25 mmol/l. Anamnesis states hereditary familial hypercholesterolemia caused by synthesis disruption of receptor-related proteins for:
- A. High-density lipoproteins
- B. Very low-density lipoproteins
- C. Middle-density lipoproteins
- D. Chylomicrons
- E. Low-density lipoproteins
Hint
Think about which cholesterol-carrying particle is normally cleared from plasma by receptor-mediated uptake into cells, and what builds up in blood when that uptake fails.
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