KROK 1 2015 – Question 96 · KROK (Medicine) · Pathomorphology

A patient with high-titer antinuclear antibodies died from progressing renal impairment. Autopsy revealed mesangioproliferative glomerulonephritis and abacterial polypous endocarditis. Periarterial bulbar sclerosis was detected in spleen and productive proliferative vasculitis in skin. What is the most likely diagnosis?

  1. A. Nephrotic syndrome
  2. B. Systemic lupus erythematosus
  3. C. Periarteritis nodosa
  4. D. Rheumatism
  5. E. Dermatomyositis
Hint

Ask which single autoimmune disease with antinuclear antibodies can damage the kidney, heart valves, spleen and skin at the same time, and which lesions are typical of it.

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