KROK 1 2015 – Question 1 · KROK (Medicine) · Biological Chemistry

Characteristic sign of glycogenosis is muscle pain during physical work. Blood examination usually reveals hypoglycemia. This pathology is caused by congenital deficiency of the following enzyme:

  1. A. γ-amylase
  2. B. Glycogen phosphorylase
  3. C. Glucose 6-phosphate dehydrogenase
  4. D. α-amylase
  5. E. Lysosomal glycosidase
Hint

Think about which step in the mobilisation of stored glycogen would be defective if exercising muscle cramps and blood sugar also falls.

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