KROK 1 2014 – Question 52 · KROK (Medicine) · Pathophysiology
Diabetic nephropathy with uremia has developed in a patient with pancreatic diabetes. The velocity of glomerular filtration is 9 ml/min. What mechanism of a decrease in glomerular filtration velocity and chronic renal failure development is most likely in the case of this patient?
- A. Reduction of active nephron mass
- B. Decrease in systemic arterial pressure
- C. Arteriolar spasm
- D. Tissue acidosis
- E. Obstruction of nephron tubules with hyaline casts
Hint
Consider what long-standing diabetic damage to the glomeruli does to the overall filtering capacity of the kidneys, and what distinguishes a chronic fall in filtration from a reversible one.
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