KROK 1 2014 – Question 117 · KROK (Medicine) · Pathophysiology

Examination of a 56-year-old female patient with a history of type 1 diabetes revealed a disorder of protein metabolism that is manifested by aminoacidemia in the laboratory blood test values, and clinically by the delayed wound healing and decreased synthesis of antibodies. Which of the following mechanisms causes the development of aminoacidemia?

  1. A. Increased proteolysis
  2. B. Increase in low-density lipoprotein level
  3. C. Decrease in the concentration of amino acids in blood
  4. D. Albuminosis
  5. E. Increase in the oncotic pressure in the blood plasma
Hint

Ask what insulin normally does to protein turnover in tissues, and what happens to the pool of free amino acids in the blood when that influence is missing.

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