KROK 1 2014 – Question 80 · KROK (Medicine) · Pathophysiology

A patient is diagnosed with iron-deficiency sideroachrestic anemia, progression of which is characterised by skin hyperpigmentation, pigmentary cirrhosis, heart and pancreas affection. Iron level in the blood serum is increased. What disorder of iron metabolism causes this disease?

  1. A. Increased iron assimilation by body
  2. B. Excessive iron intake with food
  3. C. Disorder of iron absorption in bowels
  4. D. Failure to assimilate iron leading to iron accumulation in tissues
  5. E. -
Hint

Serum iron is high and organs show iron-related damage, so ask whether the defect lies in how much iron enters the body or in what the cells can do with it.

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