KROK 1 2013 – Question 124 · KROK (Medicine) · Biological Chemistry
Diseases of the respiratory system and circulatory disorders impair the transport of oxygen, thus leading to hypoxia. Under these conditions the energy metabolism is carried out by anaerobic glycolysis. As a result, the following substance is generated and accumulated in blood:
- A. Pyruvic acid
- B. Lactic acid
- C. Fumaric acid
- D. Citric acid
- E. Glutamic acid
Hint
Without oxygen the cell must regenerate NAD+ so that glycolysis can keep going; think about which reduction of the glycolytic end product does this and why its product can disturb blood pH.
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