KROK 1 2013 – Question 18 · KROK (Medicine) · Pathomorphology

Autopsy of the patient revealed bone marrow hyperplasia of tubular and flat bones (pyoid marrow), splenomegaly (6 kg) and hepatomegaly (5 kg), enlargement of all lymph node groups. What disease are the identified changes typical for?

  1. A. Chronic lymphocytic leukemia
  2. B. Hodgkin’s disease
  3. C. Polycythemia vera
  4. D. Multiple myeloma
  5. E. Chronic myelogenous leukemia
Hint

Combine the pus-like marrow in long and flat bones with a massively enlarged spleen and liver, and ask which proliferating cell line explains such organ infiltration.

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