KROK 1 2013 – Question 42 · KROK (Medicine) · Pathomorphology

A male patient is 28 years old. Histological study of a cervical lymph node revealed a change of its pattern due to the proliferation of epithelioid, lymphoid cells and macrophages having nuclei in form of a horseshoe. In the center of some cell clusters there were non-structured light-pink areas with fragments of nuclei. What disease are these changes typical for?

  1. A. Syphilis
  2. B. Actinomycosis
  3. C. Tuberculosis
  4. D. Hodgkin’s disease
  5. E. Tumor metastasis
Hint

Think about the type of necrosis found in the centre of an epithelioid-cell cluster with horseshoe-nucleated giant cells, and which chronic infection produces that picture.

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