KROK 1 2012 – Question 180 · KROK (Medicine) · Pathomorphology
A patient with high-titer antinuclear antibodies died from progressing renal impairment. Autopsy revealed mesangioproliferative glomerulonephritis and abacterial polypous endocarditis. There was periarterial bulbar sclerosis in spleen and productive proliferative vasculitis in skin. What is the most likely diagnosis?
- A. Systemic lupus erythematosus
- B. Dermatomyositis
- C. Nephrotic syndrome
- D. Rheumatism
- E. Periarteritis nodosa
Hint
Combine the serological marker with the pattern of kidney, heart-valve, splenic and skin vascular lesions, and ask which immune-complex multi-organ disease produces them all.
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