KROK 1 2012 – Question 154 · KROK (Medicine) · Pathomorphology
A 50 year old patient has been taking treatment thrice for the last 6 months because of fractures caused by domestic accidents. Microscopical examination of bony tissue revealed foci of lacunar resolution, giant-cell granulomas in the tumour-like formations, cysts. Bony tissue was substituted by fibrous connective tissue. Examination revealed also adenoma of parathyroid gland and hypercalcemia. What is the most probable diagnosis?
- A. Myelomatosis
- B. Parathyroid osteodystrophy
- C. Osteopetrosis
- D. Osteomyelitis
- E. Paget’s disease
Hint
Connect the bone changes and the raised blood calcium to the endocrine tumour that was found, and ask what excess of that gland's hormone does to bone turnover.
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