KROK 1 2012 – Question 78 · KROK (Medicine) · Pathophysiology
From the group of children who were eating sweet sappy watermelon two kids developed the signs of poisoning: rapid weakness, dizziness, headache, vomiting, edema, tachycardia, cyanosis of mouth, ears, tips of the fingers cyanosis. High concentration of nitrates was detected. What is the leading mechanism of the pathogenesis of the poisoning in the two children?
- A. Block cytochrome oxidase
- B. Insufficiency of superoxide dismutase
- C. Insufficiency of catalase
- D. Insufficiency of met-Hb-reductase
- E. Insufficiency glutathione peroxidase
Hint
Cyanosis after nitrate exposure points to a haemic type of hypoxia; think about what happens to haemoglobin iron and why only some children are affected.
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