KROK 1 2011 – Question 59 · KROK (Medicine) · Pharmacology

A child suffers from drug idiosyncrasy. What is the cause of such reaction?

  1. A. Inhibition of microsomal liver enzymes
  2. B. Exhaustion of substrate interacting with pharmaceutical substance
  3. C. Associated disease of target organ
  4. D. Hereditary enzymopathy
  5. E. Accumulation of pharmaceutical substance
Hint

Recall that idiosyncrasy is an abnormal, qualitatively unusual reaction that appears on first exposure and is independent of dose; ask what in the patient's own constitution could cause that.

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