KROK 1 2011 – Question 102 · KROK (Medicine) · Pharmacology

A patient with acute myocardial infarction has been administered heparin as a part of complex therapy. Some time after heparin injection the patient developed hematuria. What heparin antagonist should be injected in order to manage the complication?

  1. A. Protamine sulfate
  2. B. Fibrinogen
  3. C. Vicasol
  4. D. Neodicumarin
  5. E. Aminocaproic acid
Hint

Heparin is a strongly negatively charged molecule; ask which kind of agent would bind and neutralise it directly rather than act on the clotting pathways.

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