KROK 1 2011 – Question 54 · KROK (Medicine) · Pathomorphology

A worker of a cattle farm fell acutely ill and then died from the progressing intoxication. Autopsy revealed enlarged, hyposthenic spleen of dark-cherry colour when dissected; excessive pulp scraping. At the base and fornix of brain pia maters are edematous, soaked with blood, dark-red ("scarlet hat"). Microscopic examination revealed serous haemorrhagic inflammation of brain tissues and tunics along with destruction of small vessel walls. What is the most likely diagnosis?

  1. A. Tularemia
  2. B. Anthrax
  3. C. Cholera
  4. D. Plague
  5. E. Brucellosis
Hint

Combine the occupational exposure to livestock with the characteristic gross appearance of the spleen and the haemorrhagic change of the meninges to decide which zoonosis kills this quickly.

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