KROK 1 2011 – Question 87 · KROK (Medicine) · Pathomorphology
Examination of a pregnant woman having Rh-negative blood revealed high level of antierythrocytic antibodies. For its reduction she was implanted with her husband’s Rh-positive skin graft. The graft was rejected in two weeks. Its microscopic examination revealed circulatory disturbance, edema and cellular infiltration with lymphocytes, neutrophils and macrophages predominance. What is the most likely pathology?
- A. Delayed-type hypersensitivity
- B. Granulomatous inflammation
- C. Interstitial inflammation
- D. Graft immunity
- E. Immediate hypersensitivity
Hint
Focus on what is being transplanted: ask why tissue from a genetically different person, carrying foreign antigens, meets a lymphocyte-rich attack within about two weeks.
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