KROK 1 2011 – Question 46 · KROK (Medicine) · Pathomorphology

Microscopical examination of an enlarged cervical lymph node revealed blurring of its structure, absence of lymphoid follicles; all the microscopic fields showed cells with roundish nuclei and thin limbus of basophil cytoplasm. It is known from the clinical data that other groups of lymph nodes are also enlarged as well as spleen and liver. What disease might be suspected?

  1. A. Myeloid leukosis
  2. B. Lymphoid leukosis
  3. C. Lymphosarcoma
  4. D. Lymphogranulomatosis
  5. E. Multiple myeloma
Hint

Weigh the monotonous small round cells with effaced architecture and enlargement of many nodal groups, spleen and liver, and decide which cell lineage is proliferating systemically.

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