Question 50 (part 2) · LEK · Hepatocellular carcinoma (HCC)

Screening for hepatocellular carcinoma (HCC) involves:

  1. A. an ultrasound and alpha-fetoprotein measurement every 12 months in high-risk patients i.e. those with cirrhosis caused by hepatitis B and C, hemochromatosis, alcohol.
  2. B. an ultrasound and alpha-fetoprotein measurement every 6 months in high-risk patients i.e. those with cirrhosis caused by hepatitis B and C, hemochromatosis, alcohol.
  3. C. an ultrasound and alpha-fetoprotein measurement every 6 months in high-risk patients i.e. those with cirrhosis caused by hepatitis B and C, hemochromatosis, but not alcohol.
  4. D. an ultrasound and alpha-fetoprotein measurement every 12 months in high-risk patients i.e. those with cirrhosis caused by hepatitis B and C, hemochromatosis, but not alcohol.
  5. E. an ultrasound and alpha-fetoprotein measurement every 12 months in high-risk patients i.e. those with cirrhosis caused only by hepatitis B and C.
Hint

Recall the surveillance interval derived from HCC doubling time, and ask whether the cause of cirrhosis matters.

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